Stem-cell treatment

PREPARATION

Before stem cell treatment, individuals or donors, if available, are evaluated for heart, liver and lung diseases. For this evaluation, individuals are first asked for anamnesis information. Then blood test, urine test, Hepatitis and infection test are performed. If deemed necessary, imaging tests may be requested. The final anesthesiologist consultation happens.
Extra tests tests could be required to be conducted in case patient has any other existing or underlying medical condition.

We endevaour to evaluate all possible risk factors by carefully dissecting all individual biological and clinical parameters in terms of conducting wide range of tests and gathering all records pertaining patients past medical and current conditions.

ANESTHESIA

Type of anaesthesia is determined in terms of the scale of the areas aimed to be treated.
Local anaesthesia are the most common types of anaesthesia.

STEM-CELL TREATMENT TECHNIQUE

Stem cells are usually obtained from bone marrow and fat tissues. Fat tissues are especially rich in stem cells, and stem cells obtained from fat tissues are more durable. Stem cells from fat tissues are more easily collected, isolated and multiplied. For this reason, it is preferred for fat removal from the abdominal area, hip or outer thigh of donors or individuals. The area where the stem cells will be taken is anesthetized with local anesthesia. Then, fat removal begins with special 30 ml syringes. The oils obtained are not transferred from the syringe to another location and are sterilized 3 times. After sterilization, it is kept closed for 30 minutes. During the waiting process, oils are separated into liquid and precipitate. The liquid part of the separated oils is discarded and the sediment part is sent to the laboratory in a sterile manner in syringes. As a final procedure, the oils in the syringe coming from the laboratory are injected into the area to be treated and the process is completed.

 

• STEM-CELL TREATMENT IN NEUROLOGICAL DISEASES

1. Amyotrophic Lateral Sclerosis (ALS)

This disorder, known as muscle wasting, causes spinal cord damage. It is the loss of neurons in the spinal cord, brainstem and central nervous system. The stem cells to be used are determined according to the patient’s age and weight. Stem cells are usually taken from the individual’s bone marrow or blood tissue (autologous cells). The stem cells taken are processed in a laboratory environment and injected into the patient. It is usually performed in 3 sessions, 4 weeks or 45 days apart.

2. Autism

As a neurobiological disorder, autism is a disorder of repetitive behavior, communication and social behavior that develops due to differences in functioning of the brain and nervous system. The stem cells to be used for this disease are determined according to the age and weight of the patients. Individuals’ own stem cells are used. Stem cells are collected from the bone marrow or as mesenchymal stem cells. The collected stem cells are processed in a laboratory environment and injected into the individual. This treatment is applied in 3 sessions at 4-week or 45-day intervals.

3. Cerebral Palsy (CP)

It is a permanent movement and posture disorder caused by brain damage or abnormalities in brain development. The number of stem cells to be administered in this disease is determined according to the age and weight of the individual. Cells are taken from the individual. Stem cells are taken by the mesenchymal stem cell (removal from bone marrow and fat tissue) method. The collected stem cells are processed in a laboratory environment and injected into the individual. In this disease, stem cell treatment is applied in 3 sessions at 4-week or 45-day intervals.

 

4. Alzheimer’s Disease

Alzheimer’s disease is a neurological disease that causes memory loss, dementia and decreased cognitive functions due to the death of brain cells over time. The number of stem cells to be applied is determined according to the age and weight of the individual. Stem cells are collected from the individual using the mesenchymal stem cell (taken from bone marrow or fat tissue) method. The collected stem cells are processed in a laboratory environment and injected into the individual. This treatment is applied in 3 sessions at 4-week or 45-day intervals.

 

5. Multiple Sclerosis (MS)

It is an autoimmune disorder. It is when the immune system attacks the body’s own nerve cells, causing inflammation. The number of stem cells to be administered is determined according to the age and weight of the individual. Stem cells are taken from the individual. It is collected from bone marrow or fat cells (mesenchymal stem cell method). The collected stem cells are grown in a laboratory environment and injected into the individual. This treatment is applied in 3 sessions at 4-week or 45-day intervals.

 

• STEM-CELL TREATMENT IN GASTROINTESTINAL DISEASES

1. Ulcerative Colitis

It is an inflammatory disorder in which there is inflammation of the colon mucosa on the inner surface of the large intestine. Stem cells in this disease are obtained from the patient’s bone marrow or blood. Or it is performed with allogeneic stem cells (stem cells taken from a compatible donor). The collected stem cells are processed in a laboratory environment and can be frozen before being injected into the patient. It is then injected directly into the tissue or organ. In this way, the progression of the disease is slowed down by strengthening the immune system.

2. Crohn’s Disease

It is inflammation of the gastrointestinal tract from the mouth to the anus. It is usually seen in the cecum, the beginning region of the large intestine, and the ileum, the last part of the small intestine. It is usually taken from the patient’s own bone marrow, fat tissue and blood cells. Or stem cells taken from a suitable donor can be used with the allogeneic method. The collected stem cells are processed and purified in the laboratory and injected into the individual. It is aimed to repair damaged tissues and strengthen the immune system.

3. Cirrhosis (Liver Failure)

It is a serious liver disease in which the liver is permanently damaged as a result of healthy liver tissue being replaced by scar tissue. Stem cells obtained from the individual’s own bone marrow or blood, which are autologous cells, are used. The collected stem cells are processed in a laboratory environment and injected into the patient. The repair of liver tissue is aimed with the help of injected stem cells.

 

• STEM-CELL TREATMENTS IN ORTHOPEDIC DISEASES

 

1. Non-Union Fractures

It is the situation where the broken pieces do not come together despite the time that has passed since the breakage occurred. It is performed on autologous cells taken from individuals themselves. Stem cells are collected from the bone marrow. The collected stem cells are processed in a laboratory environment and injected into the non-healing fracture area. Thus, stem cells can help repair bone tissue.

2. Degenerative Disc Disease

These are pains that occur due to the development of abnormalities in the spinal discs due to joint wear and tear with advancing age. In stem cell therapy, stem cells (autologous cells) taken from the patient are used. Stem cells taken from individuals’ bone marrow are processed in the laboratory. The processed stem cells are injected into the degenerative disc area. Thus, stem cells support structural integrity and healing.

3. Osteoarthritis

It is the calcification that occurs in the joints over time. Stem cells taken from individuals themselves are used. Stem cells are usually collected from bone marrow or fatty tissue (mesenchymal stem cell). The collected stem cells are processed in a laboratory environment and injected into the damaged area. Thus, it is aimed to improve joint function.

4. Meniscus Tear

It is the damage to the cartilage tissue in the knee. It is aimed to heal the damaged cartilage tissue. Stem cells collected from the patient’s bone marrow or fat cells are used. The collected stem cells are processed in a laboratory environment and injected into the meniscus area where the tear is located.

5. Carpal Tunnel Syndrome

It is pain, numbness and weakness that occurs as a result of pressure on the median nerve, which is located in the middle of the wrist and distributes to the first 3 fingers. It is done with the help of autologous stem cells taken from the patient himself. Stem cells are collected from individuals’ fatty tissues or bone marrow (mesenchymal stem cells). The collected stem cells are processed in a laboratory environment and injected into the area where the carpal tunnel is located. The aim is to relax the carpal tunnel nerve.

6. Bursitis

It is inflammation, swelling or irritation of the fluid sacs that act as a buffer between bone, tendon and skin tissues. In the treatment of this disease, stem cells are collected from the patient’s bone marrow or fatty tissues. The collected stem cells are processed in a laboratory environment. And it is injected into the irritated area. The aim here is to reduce symptoms and support the healing process.

7. Avascular Necrosis

This disease, also called osteonecrosis, is the death of bone tissue due to insufficient blood flow. The stem cells to be used in this disease are made with autologous cells taken from the patient himself. Stem cells are collected from bone marrow or fat tissue and processed in the laboratory. The resulting stem cells are injected into the area where necrosis occurs. The aim here is to repair the damage and ensure the formation of new vessels.

8. Tendonopathy

They are inflammation and micro tears that occur in tendons. It is aimed to restore the functionality of tendons. Autologous cells taken from the patient are used. Stem cells collected from bone marrow or fat tissue are processed in a laboratory environment. The resulting stem cells are injected into the damaged tendon.

• STEM-CELL TREATMENT IN GYNECOLOGICAL DISEASES

1. Thin Endometrium and Asherman Syndrome

Thin endometrium is when the uterine wall is thinner than normal. Asherman Syndrome is the closure of part or all of the uterine cavity as a result of adhesions formed in the uterus. It is performed with autologous stem cells collected from the bone marrow or fat tissue of individuals. The collected stem cells are processed in the laboratory environment and injected into the uterine wall. The purpose here is to renew and heal the uterine wall.

2. Decreased Oocyte Reserve

Decreased ovarian reserve is when the ovaries begin to lose their ability to produce normal eggs and the pregnancy rate decreases. It is aimed to repair the ovarian tissue. It is performed with autologous cells collected from individuals. Stem cells taken from bone marrow or blood cells are processed in a laboratory environment and injected into the ovaries.

• STEM-CELL TREATMENT IN UROLOGICAL DISEASES

1. Erectile Dysfunction

It is a sexual dysfunction that occurs in male individuals. The aim is to restore sexual function by increasing blood flow to the penis. Stem cells collected from individuals’ own bone marrow or fat tissues (mesenchymal stem cells) are processed in a laboratory environment. It is then injected into the area where sexual function is regulated.

• STEM-CELL TREATMENT IN DERMATOLOGICAL DISEASES

Fibroblasts are used in stem cell treatment of dermatological diseases. Fibroblasts are types of cells found in connective tissues and produce collagen and proteins that help the skin maintain its elasticity and stay strong. Fibroblasts are used to create skin grafts and provide repair. Fibroblasts are usually collected and stored for future use.

1. Scars and Burns

Stem cells can be used for burns and scars. However, in order to benefit from stem cells, the condition of wounds and burns must be determined, and stem cell treatment cannot always be applied. For burns and scars, it can be done in two ways: skin grafts created with fibroblast cells or injecting stem cells into the damaged area to accelerate the healing process.

2. Wounds That Don’t Heal

Stem cell treatment can be applied to non-healing wounds such as diabetic foot, venous ulcer and Buerger’s disease. However, stem cell treatment may not be applied to every individual. The application of stem cell therapy is decided according to the wound condition and the general health of the individual. Stem cells collected from the individual’s bone marrow or fat tissues are processed in the laboratory and then injected into the wound area. Injected stem cells support wound healing by regenerating blood vessels in the wound area and increasing oxygen in the wound area.

3. Filling of Skin Deformities

Stem cell therapy can be used to fill the deformations in the skin. It can be done either by transplanting skin grafts consisting of fibroblasts to deformed areas or by injecting stem cells collected from the person’s own bone marrow or fat tissue and processed in the laboratory. The aim here is to increase healing in deformed areas.

4. Skin Rejuvenation

Today, stem cells are also used to reduce skin wrinkles, sagging and other signs of aging. Here, the regenerative properties of stem cells are used. It is performed by processing stem cells collected from the individual’s own bone marrow or fat cells in the laboratory and injecting them into the damaged area. Or stem cells obtained from fibroblast cells can be used. Here, the aim is to preserve the elasticity and strength of the skin and renew the skin tissue by using the renewal feature of stem cells.

• STEM-CELL TREATMENT IN EYE DISEASES (OPTHALMOLOGICAL DISEASES)

1. Corneal Damage

The cornea is a transparent, dome-shaped structure located in the front part of the eye. Impacts to the eye, infections and some diseases damage the corneal layer and may cause a decrease or complete loss of vision. Stem cells collected from individuals’ own bone marrow or fat tissue or stem cells taken from suitable donors (allograft) are processed in the laboratory. It is then injected into the eye under local anesthesia into the cornea. It is a surgical procedure. The aim is to make the cornea transparent again and repair it.

2. Macular Degeneration

It is a genetic retinal disease caused by the deterioration of the macular region of the eye, known as macular degeneration. Stem cells collected from individuals’ own bone marrow or fat tissue or stem cells taken from suitable donors (allograft) are processed in the laboratory. It is then injected into the eye under local anesthesia into the cornea. It is a surgical procedure. It is aimed to improve visual function.

• STEM-CELL TREATMENT IN RHEUMATOLOGICAL DISEASES

1. Systemic Lupus Erythematosus (SLE)

It is a rheumatic disease that affects many organs in the body. It is when the body’s immune system attacks its own cells. Stem cells collected from the individual’s bone marrow or blood cells are processed in the laboratory. It is then injected into the areas affected by the disease. The goal here is to support tissue repair and reduce inflammation.